Knowledge: Lemon Lime (Citrus limon & Citrus microcarpa)

October 5, 2024 | by bionutriciaadmin

Citrus limon + Citrofortunella microcarpa

Lemon and lime are major fruit species from citrus family. The pulp and rind are commonly used in cooking and baking, while the juice (pH 2.2) gives refreshing sour taste to cuisine and beverages. The acidic juice of these citrus fruits is also used to improve food texture such as in macerating berries, tenderizing meat and to reduce greasiness of a dish.

The combination of lemon and lime gives a sour and slightly tangy sweet flavour that is suitable to be used as flavour enhancing ingredient in culinary. This combination offers greater source of nutritional values by providing rich source of Vitamin C. Extracts of these fruits were reported to have many beneficial effects including anticancer effects, antibacterial properties, reducing risk of hypertension, mental health problems, respiratory problems, arthritis, and rheumatism.

We provide practical, easy & consistent on food processing application.Fresh natural flavor extract powder for Bakery & Beverage.

Vegan
Non-GMO
No Fillers
No Flavors
No Additives
No Artificial Colors
Soy and Gluten Free
Lab Tested for Authentic & Active Compound
Origin from Malaysia Borneo Forest

	Bionutricia Lemon Lime Extract	BRAND X
Certification	Registered with the Ministry of Health, Halal Tested	Not registered & certified
Raw Ingredients	Lemon Citrus limon & Lime Citrus microcarpa from Malaysia farm	Very little / no raw ingredients; Use non-Lemon Calamansi materials
Process	Extracted through R.O. water & Ultra-sonic; Full bio-active ingredients	Grinded peel powder; Extracted through ethanol process
Active Compound	0.5-1% Bioflavonoids	Not Tested
Formulation	Only Lemon Lime which is proven safe and effective	Combination of other ingredients (effectiveness & safety is not proven); Added with prohibited drugs
Label	Transparent, standardized Lemon Citrus limon & Lime Citrus microcarpa extract 0.5-1% bioflavonoids	Misleading claim (quantity), incorrect amount of Lemon Calamansi extract, mostly filler ingredients

High Standard Product Quality Control

HEALTH BENEFITS

Improves collagen synthesis

In vitro studies of Ascorbic acid

Subject

Human skin fibroblast cell line

Duration of the study

5 days

Groups

Control
100 µM AA

Parameters analysed

Collagen I and IV expression level and synthesis of type I procollagen

Outcomes

Vitamin C enhanced the expression levels of collagen I and IV in human skin fibroblast and increased the type I procollagen synthesis.

Table 1: Effect of ascorbic acid (AA) on type I and IV collagen expression level in human fibroblast cells.

Legends: white bar = without AA; black bar = with 100 µM AA

Table 2: Effect of ascorbic acid (AA) on type I procollagen synthesis in human fibroblast cells.

Legends: white bar = without AA; black bar = with 100 µM AA

Function

-Vitamin C is essential for collagen biosynthesis. -High content of Vitamin C and flavonoids act as good source of antioxidants, antibiotic and disinfectants which are beneficial for skin health maintenance.

Antitumor properties

In vivo studies of Citrus flavonoids

Subject

Female Syrian golden hamsters (n = 60)

Duration of the study

1 week

Groups

Control (DMSO)
2.5% hesperetin
2.5% neohesperidin
2.5% of naringenin
2.5% of naringin

Parameters analysed

Average tumor burden in mm3

Outcomes

All treatments with citrus flavonoids have reduced tumor burden in hamsters, and tumor volume reduction is significantly different between Group 1 and 5.

Group	Average tumor burden (mm3)
1	269 ± 75
2	191 ± 47
3	222 ± 43
4	188 ± 55
5	77.1 ± 30

*Group 1 = untreated *Group 2,3,4,5 = treated with citrus flavonoids

Function

High content of flavonoids in citrus fruits may have antitumor properties and give protection effect against cancer.

Prevents kidney stone formation

Long-term lemonade therapy in patients

Subject

Hypocitraturic nephrolithiasis patients (n = 32)

Duration of the study

24 hours (Urine analysis) >1 year (Stone formation)

Groups

Control (Potassium Citrate)
Lemonade

Parameters analysed

Urinary citrate level and stone size

Outcomes

-Lemonade therapy increased the urinary citrate level, similar to the effect of potassium citrate. -Stone formation rate was found decreased in patients with lemonade therapy. GroupControl (Potassium citrate)Lemonade

Table 1: Urinary profiles of control and lemonade therapy after 24 hours.
	Urinary analysis
	Pre-therapy	Post-therapy	Pre-therapy	Post-therapy
Vol (mL)	2098	2488	1942	2354
Sodium (mg/day)	132	163	155	186
Uric acid (mg/day)	468	639	455	533
Oxalate (mg/day)	28	35	27	28
Citrate (mg/day)	349	831	350	733

Pre-treatmentPost-treatment

Table 2: Stone size of control and lemonade therapy.
	Lemonade
Mean of stone burden (mm2)	37.2	30.4

Function

The high content of dietary citrate in citrus fruits can have citraturic effect and reduces the risk of kidney stone formation.

Reduces risk of inflammatory polyarthritis

Prospective, population-based, nested case-control study

Subject

Individuals with and without inflammatory polyarthritis (IP) aged 45-74 years

Duration of the study

7 days

Groups

(1) Control (n = 146) (2) Individuals with inflammatory polyarthritis (IP) (n = 73)

Parameters analysed

Diet intake diary and development of inflammatory polyarthritis

Outcomes

Table 1: Association between dietary vitamin C and IP.
	Association between dietary vitamin C and IP
	Control group, no. (%)	IP group, no. (%)	Adjusted odd ratio (95% CI)	p value
Vitamin C (< 40 mg)	10 (7)	15 (21)	3.9 folds	0.01 (significant difference)
Vitamin E 1, <5.3 mg 2, 5.3-7.7 mg *3, >7.7 mg	26 (36) 27 (37) *20 (27)	47 (32) 46 (32) *53 (36)	1.3 folds 1.6 folds *1fold	0.5 (no significant difference)

People who consumed less than 56 mg of vitamin C daily (above the current UK RNI of 40 mg/day) had a more than threefold increase in the risk of IP compared with those who consumed more.

Function

Vitamin C is an important antioxidant micronutrient that may act as primary prevention of inflammatory polyarthritis.

Standardized Pure 20:1 Lemon Lime Powder Extract

Pure 20:1 Lemon Lime Extract
0.5-1% Bioflavonoids (Bioactive Phytochemicals)
Ultrasonic solvent extraction
Rich in phytonutrient
High in antioxidant
For general health purpose
Promotes hydration
Good source of vitamin C
Supports weight loss
Promotes skin health
Aids digestion
Scientifically tested

View all