Chayote (Labu Siam/ Siem), also known as mirliton squash or chocho is one kind of squash that belongs to the gourd family (Cucurbitaceae), originated from Mexico and Latin America but it is now cultivated all around the world.
Chayote is famous for its high nutrients and is a great source of antioxidants. It can be eaten raw or cooked. Chayote is slightly sweet and has taste similar to cucumber. Common recipe for chayote including salads and salsas.
Rich in nutrients
Good source of Vitamin C and Vitamin B9 (folate)
Source of antioxidants
Antihypertensive effect
Reduce blood sugar level
Support healthy pregnancy
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HEALTH BENEFITS
Antihypertensive properties
Bivariant analysis
Subject
Elderly with hypertension (n = 360)
Group
Before intervention
After intervention
Duration
4 days
Dosage
Chayote juice (122 grams of chayote, prepared 180 ml of plain water) – taken an hour or 2 hour before meal
Parameters analyzed
Blood pressure measurement
Outcomes
Visible benefits Consumption of chayote juice has median decrease in systolic blood 30 mmHg and diastolic 10 mmHg. Table 1: Distribution of frequency of elderly people with hypertension based on measurement blood pressure before and after drinking chayote juice.
Functions
Chayote juice has effects to reduce blood pressure in elderly with hypertension. By consuming chayote juice, it may help in maintaining and controlling blood pressure of the elderly.
Folate – improves healthy pregnancy
Population-based study
Subject
Pregnant women with or without supplementation of folic acid
Groups
Without folic acid supplementation
With folic acid supplementation
With folic acid supplementation + multivitamin
With multivitamin supplementation
Duration
From 6th to 12th weeks gestation week
Dosage
3 mg FA tablet
Parameters analyzed
Comparison of prospective medically recorded data of newborns (birth weight, preterm birth)
Outcomes
Visible benefits
The rate of preterm births (7.6%) was significantly lower in folic acid group compared with the reference sample (11.8%).
Folic acid alone is the third trimester associated with 0.6 week longer gestational age and a more significant reduction in the rate of preterm births (4.8%).
Functions
Chayote, which is rich in folic acid may be a natural source of folic acid for pregnant women.
Reduce blood sugar level
In vivo lab experiment
Subject
White male mice with DD Webster strain
Group
Negative control group
Positive control group with STZ 60mg/kgBW
Experimental group I with STZ 60mg/kgBW + EEBLS of 100 mg/kgBW
Experimental group II with STZ 60mg/kgBW + EEBLS 200mg/kgBW
*STZ = streptozotocin *EEBLS = ekstrak etanol buah labu siam
Duration
28 days
Dose
Ethanol extract of chayote at 60 – 200mg/kgBW
Parameters analyzed
Blood glucose level measurement
Outcomes
Visible benefits Ethanol extract of chayote administered either in 100 mg/kg or 200 mg/kg decrease blood glucose level in mice Figure 1: Blood glucose level in mice per week for 28 days. Chayote extract was given starting from day 5. Black arrow indicates dropping of blood glucose level.
Purple: EEBLS 200 mg Green: EEBLS 100 mg Red: positive control Blue: negative control*Diabetes is induced by streptozotocin (STZ). STZ damages pancreas b cells so that KGD increases.
Functions
200 mg/kg of chayote extract decrease blood sugar content
Antioxidant and Anti-inflammatory properties
Exploratory study
Subject
12 older adults, with an average age of 71 ± 6 years (10 women and 2 men) with a diagnosis of metabolic syndrome (MetS)
Group
Placebo
Chayote extract supplementation
Duration
6 weeks
Dosage
500 mg, 3 times per day
Parameters analyzed
Weight different between placebo and GA/HCA-supplemented group
Outcomes
Visible benefits
There was a statistically significant decrease in the concentration of lipoperoxidases together with significant increase in total antioxidant status.
The oxidative stress index (OxS-Score) showed a statistically significant decrease.
Significant decrease in the concentration of TNF-α after treatment was also noted.
Table 1: Markers of oxidative stress during pre- and post-treatment.
Table 1: Markers of inflammation during pre- and post-treatment.
Functions
The consumption of the dry fruit of chayote has an antioxidant and anti-inflammatory effect in older adults with metabolic syndrome.