White Tomato + Collagen Peptide OEM: Phytoene Standardisation, Herbosomal® Technology & Halal Formats

Direct answer: A white tomato + collagen peptide OEM formulation combines two skin-focused actives — colourless carotenoids (phytoene and phytofluene) from Solanum lycopersicum and hydrolysed collagen peptide — into a single supplement product manufactured under contract for a brand owner. At Bionutricia, this pairing is produced in liquid sachet or liquid bottle format using Herbosomal® — Bionutricia’s proprietary liposomal encapsulation and sustained-release technology (registered trademark; patent-pending PI2023005773) — which encapsulates both actives in phospholipid carriers as a manufacturing process. The white tomato fraction is standardised to phytoene and phytofluene content, while the collagen peptide is specified by molecular weight and hydroxyproline assay. Both ingredients are handled in a JAKIM Halal-certified, FSSC 22000-audited facility in Sungai Buloh, Malaysia, with full certificate-of-analysis documentation for every batch. A brand owner commissioning this formulation should specify the phytoene/phytofluene assay percentage, the collagen peptide molecular weight range, the total active load per sachet or bottle, and the desired claim language — all of which Bionutricia’s in-house R&D team (a registered pharmacist, nutritionist, dietitian and PhD biomedical scientist) can help define during formulation development.

What White Tomato Brings to the Formulation

White tomato extract is derived from selected Solanum lycopersicum varieties bred for high colourless carotenoid content — specifically phytoene and phytofluene — rather than the red lycopene that dominates conventional tomatoes. These compounds are the actives a brand owner should standardise for, because they are the markers that distinguish a white tomato extract from an ordinary tomato extract.

For OEM specification purposes, the critical parameters are:

• Assay marker: Total phytoene + phytofluene, typically expressed as a percentage of the extract
• Botanical identity: Solanum lycopersicum, with the extract ratio (e.g. 100:1) documented on the certificate of analysis
• Physical form: Fine powder, soluble in water for liquid sachet and liquid bottle applications
• Heavy metals and microbial limits: Must meet food-grade specifications under MeSTI and FSSC 22000 requirements

The existing White Tomato Extract Commercial Monograph on bionutricia.com covers the single-ingredient specification in greater depth. This article focuses on what changes when white tomato is paired with collagen peptide in a combination OEM product.

What Collagen Peptide Brings to the Formulation

Collagen peptide — also referred to as hydrolysed collagen — is an enzymatically broken-down form of collagen with a low molecular weight that makes it water-soluble and suitable for liquid formats. In a white tomato + collagen combination, the collagen peptide contributes the protein fraction while the white tomato contributes the carotenoid fraction.

For OEM specification, the critical parameters are:

• Molecular weight: Typically specified as a range (e.g. below 3000 Da), as this determines solubility and clarity in liquid formats
• Assay marker: Hydroxyproline content, the amino acid unique to collagen, expressed as a percentage
• Origin: Marine collagen is halal by default; bovine collagen requires zabiha certification. Bionutricia’s Marine vs Bovine Collagen for a Halal Supplement Brand guide covers this distinction in detail
• Protein content: Typically 90%+ on a dry basis

Herbosomal® Technology in This Formulation

Herbosomal® — Bionutricia’s proprietary liposomal encapsulation and sustained-release technology (registered trademark; patent-pending PI2023005773) — is the delivery platform that distinguishes a Bionutricia-manufactured white tomato + collagen product from a standard blended liquid. In this formulation, both the white tomato carotenoid fraction and the collagen peptide are encapsulated in phospholipid carriers — primarily sunflower lecithin — as part of the manufacturing process.

What this means for a brand owner:

• Both actives are processed into a liposomal dispersion within the liquid matrix, rather than being simply mixed as free powder
• The finished product is a liquid sachet or liquid bottle format — not a powder sachet or tablet
• The phospholipid carrier system (sunflower lecithin, MCT, glycerol) is itself a food-grade ingredient list, fully compatible with JAKIM Halal certification
• Particle size is verified through NanoVerify — Bionutricia’s nanotechnology process validation from Nanotech Malaysia

The existing Herbasomal Skinboost product knowledge page documents a finished Bionutricia complex that already contains white tomato extract and collagen peptide among its ingredients, demonstrating that this combination is an established formulation path within the Herbosomal® platform.

What the Research Shows

The clinical evidence for this formulation’s two actives has been studied separately at the ingredient level. No published human clinical trial has examined the specific combination of white tomato extract and collagen peptide as a blended product. The findings below describe each ingredient independently.

White Tomato (Phytoene and Phytofluene)

A human clinical trial published in the International Journal for Vitamin and Nutrition Research (2005) found that supplementation with tomato-based products increased serum levels of lycopene, phytofluene and phytoene in human participants, and this increase was associated with reduced UV-light-induced erythema. The study examined tomato-based products rather than isolated phytoene or phytofluene, and the specific population details are not available from the returned record (study).

A review in Nutrients (2019) examined the relationship between dietary carotenoids — including phytoene and phytofluene — and skin colouration and photoprotection, surveying the available evidence on how these compounds accumulate in skin tissue (review). A further review in Photodermatology, Photoimmunology & Photomedicine (2021) assessed clinical studies on ingestible carotenoids, including tomato-derived phytoene and phytofluene, in relation to skin protection from UV exposure (review). Both are reviews of existing literature rather than primary trials.

Collagen Peptide

A randomised, placebo-controlled, blind study published in Nutrients (2019) reported that a collagen supplement improved skin hydration, elasticity, roughness and density in human participants (PMID: 31627309; study). Another randomised, double-blind, placebo-controlled study in Nutrients (2018) found that oral intake of low-molecular-weight collagen peptide improved hydration, elasticity and wrinkling in human skin (PMID: 29949889; study). A meta-analysis published in The American Journal of Medicine (2025) reviewed clinical evidence on oral collagen peptide supplementation and its association with measures of skin aging, including hydration and elasticity (meta-analysis). These studies examined specific collagen peptide formulations and populations; the findings describe the ingredient, not any Bionutricia product or the white tomato + collagen combination.

Halal Chain and Certification

Every white tomato + collagen peptide OEM product manufactured by Bionutricia carries the full certification stack:

• JAKIM Halal — certified under OEM Kontrak Pengilangan, covering the full manufacturing chain from ingredient intake to finished product dispatch
• FSSC 22000 — Food Safety System Certification, SGS-audited and current
• GMP — Good Manufacturing Practice, pharmaceutical-grade
• HACCP — Hazard Analysis Critical Control Point, process-validated
• US FDA — registered facility (FCE / FDA filings)
• MeSTI — Makanan Selamat Tanggungjawab Industri, Ministry of Health Malaysia
• NanoVerify — Verified Nano-tech Process from Nanotech Malaysia, validating the liposomal particle-size claims in Herbosomal® products

For the collagen peptide fraction, marine collagen is halal by default and does not require additional zabiha certification. Bovine collagen, if specified, must carry zabiha certification through the supply chain. Bionutricia’s supplier documentation and JAKIM Halal certificate cover the full chain from raw material to finished sachet or bottle.

Bionutricia’s OEM products are food-classified and go through MeSTI notification. They do not require NPRA health-supplement MAL registration.

Format Options for This Combination

The white tomato + collagen peptide + Herbosomal® combination is best suited to liquid formats, where the liposomal dispersion and both water-soluble actives can be held in a stable suspension:

• Liquid sachets: Single-dose, portable, ideal for beauty-from-within positioning. The Herbosomal® liposomal dispersion is held in a liquid matrix with sunflower lecithin, MCT and glycerol.
• Liquid bottles: Multi-dose format, suitable for retail shelf presence and daily-use positioning. Requires preservative system validation and stability testing.

Both formats are within Bionutricia’s approved manufacturing capability. Powder sachets and chewable tablets are also available if a brand owner prefers a non-liquid delivery, though the Herbosomal® liposomal platform is optimised for liquid formats.

What a Brand Owner Should Specify in the Brief

When commissioning a white tomato + collagen peptide OEM formulation with Bionutricia, a brand owner should include the following in the initial brief:

1. White tomato extract spec: Phytoene + phytofluene assay percentage, extract ratio, botanical identity confirmed as Solanum lycopersicum
2. Collagen peptide spec: Molecular weight range, hydroxyproline content, origin (marine or bovine), protein content
3. Total active load: Milligrams of each active per sachet or per 30 ml bottle serving
4. Format preference: Liquid sachet, liquid bottle, or alternative
5. Claim language: What the brand intends to state on-pack and in marketing — Bionutricia’s R&D team will assess compliance against Malaysian food-supplement regulations
6. Target market: Domestic (Malaysia) or export (SEA, MENA, EU, US) — this determines the documentation pack required
7. Flavour and colour preferences: White tomato extract is naturally pale; collagen peptide is neutral. The finished liquid can be flavoured and coloured to brand specification.

Frequently Asked Questions

1. Can I use bovine collagen instead of marine collagen in this formulation?

Yes, but bovine collagen requires zabiha certification through the supply chain to maintain JAKIM Halal status. Marine collagen is halal by default and is the more straightforward choice for a halal-certified product. Bionutricia can work with either, provided the supplier documentation is complete.

2. What standardisation should I ask for on the white tomato extract?

Specify total phytoene + phytofluene content as the assay marker, expressed as a percentage of the extract. The extract ratio (e.g. 100:1) and botanical identity (Solanum lycopersicum) should also appear on the certificate of analysis. Bionutricia’s R&D team can advise on the appropriate assay level for your target active load per serving.

3. Is the Herbosomal® liposomal process validated?

Yes. Bionutricia’s liposomal manufacturing process is validated through NanoVerify — Nanotech Malaysia’s verified nano-tech process certification. Particle size is measured and documented. Herbosomal® is a registered trademark with patent PI2023005773 pending; it is Bionutricia’s proprietary liposomal encapsulation and sustained-release technology.

4. Has the white tomato + collagen combination been clinically tested as a blend?

No published human clinical trial has examined the specific combination of white tomato extract and collagen peptide as a blended product. The clinical evidence for each ingredient has been studied separately at the ingredient level. The studies cited in this article describe the individual ingredients, not a combination product or any Bionutricia formulation.

5. What documentation does Bionutricia provide for each batch?

Each batch is accompanied by a certificate of analysis covering assay markers, heavy metals, microbial limits and physical specifications for both actives. The JAKIM Halal certificate, FSSC 22000 audit records and NanoVerify validation are available for buyer review. For export markets, Bionutricia can prepare the documentation pack required by the destination country’s regulatory authority.

Ready to Commission Your Formulation?

Bionutricia’s in-house R&D team — a registered pharmacist, nutritionist, dietitian and PhD biomedical scientist — is available to help you define the specification, format and claim language for your white tomato + collagen peptide OEM product. The team operates from Bionutricia’s integrated manufacturing facility in Sungai Buloh, Malaysia, founded in 2006, serving 239+ brand partners across SEA, MENA, US and EU markets.

Contact: Email ng@bio-nutricia.com or WhatsApp +60 16-661 8510 to request a quotation and start your formulation brief.

Certifications: FSSC 22000 · GMP · HACCP · JAKIM Halal · US FDA · MeSTI · NanoVerify

Article by Bionutricia R&D Team. Last updated: 2026-09-23.